Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566308 | 1.00 | REN (0.37) | RENKDM1AMAOAMAOBPOLB | |
| SCHEMBL6044601 | 0.87 | REN (0.49) | REN | |
| SCHEMBL6044593 | 0.87 | REN (0.49) | REN | |
| SCHEMBL7562108 | 0.83 | SLC6A4 (0.39) | RENPOLB | |
| SCHEMBL7560322 | 0.83 | REN (0.39) | RENKDM1AMAOAMAOB | |
| SCHEMBL7561346 | 0.82 | SLC6A4 (0.38) | POLB | |
| SCHEMBL7562638 | 0.82 | REN (0.35) | REN | |
| SCHEMBL7569293 | 0.81 | TACR1 (0.41) | POLB | |
| SCHEMBL6041459 | 0.81 | REN (0.49) | REN | |
| SCHEMBL6042707 | 0.80 | PRMT5 (0.36) | RENKDM1AMAOAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |