Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144107 | 0.88 | POLB (0.45) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL5250880 | 0.87 | POLB (0.44) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL6207733 | 0.87 | POLB (0.53) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL3982504 | 0.87 | POLB (0.53) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL5250883 | 0.87 | POLB (0.44) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL1982237 | 0.87 | POLB (0.53) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL856258 | 0.85 | POLB (0.43) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL31648060 | 0.85 | MAPT (0.43) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL3403065 | 0.83 | POLB (0.41) | POLBLMNASMN1; SMN2GBA2L3MBTL1 | |
| SCHEMBL2913340 | 0.82 | POLB (0.47) | POLBLMNASMN1; SMN2GBA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187846-A2 | 11BETA LONG-CHAIN SUBSTITUTED ESTRATRIENES, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11BETA LONG-CHAIN SUBSTITUTED ESTRATRIENES, AND THEIR USE FOR PRODUCING MEDICAMENTS | Schering Aktiengesellschaft (DE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001000652-A2 | 11β LONG-CHAIN SUBSTITUTED ESTRATRIENES, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11β LONG-CHAIN SUBSTITUTED ESTRATRIENES, AND THEIR USE FOR PRODUCING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |