SCHEMBL7563979

SCHEMBL7563979

NCCCC[C@@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.55
ALOX15 P16050 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
KMT2A Q03164 1/20 0.49
DPP8 Q6V1X1 2/20 0.48
DPP9 Q86TI2 2/20 0.48
DPP4 P27487 1/20 0.48
GSR P00390 1/20 0.47
NOD1 Q9Y239 3/20 0.44
SLC6A5 Q9Y345 1/20 0.44
CPB2 Q96IY4 4/20 0.43
DPP7 Q9UHL4 1/20 0.43
SLC15A2 Q16348 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
LNPEP Q9UIQ6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5334900 1.00 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL30148762 1.00 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL397257 1.00 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL27767761 0.98 FOLH1 (0.54) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL30731560 0.97 FOLH1 (0.52) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL5336140 0.94 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL5336146 0.94 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL32690574 0.93 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL31376469 0.92 FOLH1 (0.48) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL31376475 0.92 FOLH1 (0.48) FOLH1ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002080970-A1 METHOD FOR INHIBITING ARTICULAR CARTILAGE MATRIX CALCIFICATION REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-10-17 WO disclosed