SCHEMBL5334900

SCHEMBL5334900

NCCCCC(NC(=O)C(N)CCC(N)=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.55
ALOX15 P16050 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
KMT2A Q03164 1/20 0.49
DPP8 Q6V1X1 2/20 0.48
DPP9 Q86TI2 2/20 0.48
DPP4 P27487 1/20 0.48
GSR P00390 1/20 0.47
NOD1 Q9Y239 3/20 0.44
SLC6A5 Q9Y345 1/20 0.44
CPB2 Q96IY4 4/20 0.43
DPP7 Q9UHL4 1/20 0.43
SLC15A2 Q16348 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
LNPEP Q9UIQ6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7563979 1.00 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL30148762 1.00 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL397257 1.00 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL27767761 0.98 FOLH1 (0.54) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL30731560 0.97 FOLH1 (0.52) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL5336140 0.94 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL5336146 0.94 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL32690574 0.93 FOLH1 (0.55) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL31376469 0.92 FOLH1 (0.48) FOLH1ALOX15BLMPMP22KMT2A
SCHEMBL31376475 0.92 FOLH1 (0.48) FOLH1ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 US claimed
WO-2022140565-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES (US) 2022-06-30 WO claimed
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 US disclosed
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-04-20 US disclosed
EP-4074694-A1 AMINO ACID-, PEPTIDE- AN POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AN USES THEREOF Massachusetts Institute Of Technology (US) 2022-10-19 EP disclosed
WO-2022140565-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES (US) 2022-06-30 WO disclosed
CN-111560049-B Zwitterionic polypeptide and derivative thereof and nano-drug based on zwitterionic polypeptide and derivative 浙江大学 2022-05-17 CN disclosed
EP-3789043-A1 EXTRACTION OF PLANT SOURCE \"MEDICINAL SOUP\" AND MANUAL PREPARATION OF \"HERBAL MEDICINE\" AND RELATED PRODUCTS Institute of Basic Medical Sciences, Chinese Academi of Medical Sciences (CN) 2021-03-10 EP disclosed
US-20200330501-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-10-22 US disclosed
CN-111560049-A Zwitterionic polypeptide and derivative thereof and nano-drug based on zwitterionic polypeptide and derivative 浙江大学 2020-08-21 CN disclosed
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) 2020-06-16 US disclosed
US-20060217321-A1 Compositions to improve tic disorders TAIYOKAGAKU CO., LTD. (JP) 2006-09-28 US disclosed
US-20040058400-A1 Multivalent and multispecific binding proteins, their manufacture and use MEDICAL RESEARCH COUNCIL 2004-03-25 US disclosed
US-6492123-B1 POLYPEPTIDES COMPRISING A FIRST DOMAIN OF AN IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION, AND A SECOND DOMAIN OF AN IMMUNOGLOBULIN LIGHT CHAIN VARIABLE REGION, LINKED BUT INCAPABLE OF ASSOCIATING WITH EACH OTHER; ASSAY FOR ANTIGEN MEDICAL RESEARCH COUNCIL (GB) 2002-12-10 US disclosed
EP-0672142-B1 MULTIVALENT AND MULTISPECIFIC BINDING PROTEINS, THEIR MANUFACTURE AND USE MEDICAL RES COUNCIL (GB) 2001-02-28 EP disclosed
US-5837242-A POLYPEPTIDES MEDICAL RESEARCH COUNCIL (GB) 1998-11-17 US disclosed
EP-0726956-A1 NOVEL HUMAN TRANSGLUTAMINASES ZYMOGENETICS, INC. (US) 1996-08-21 EP disclosed
EP-0672142-A1 MULTIVALENT AND MULTISPECIFIC BINDING PROTEINS, THEIR MANUFACTURE AND USE MEDICAL RESEARCH COUNCIL (GB) 1995-09-20 EP disclosed
WO-1994013804-A1 MULTIVALENT AND MULTISPECIFIC BINDING PROTEINS, THEIR MANUFACTURE AND USE MEDICAL RESEARCH COUNCIL (GB) 1994-06-23 WO disclosed
WO-1993013207-A2 NOVEL HUMAN TRANSGLUTAMINASES ZYMOGENETICS, INC. (US) 1993-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200330501-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 FOLH1 823/4885ALOX15 1629/4885BLM 1004/4885
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 FOLH1 823/4885ALOX15 1629/4885BLM 1004/4885
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof APLNR, NPPA, ARGLU1 FOLH1 823/4885ALOX15 1629/4885BLM 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.