Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489742 | 1.00 | DPP4 (0.59) | DPP4ALDH1A1TSHRHSD17B10DPP8 | |
| SCHEMBL8074088 | 0.75 | DPP4 (0.65) | DPP4 | |
| Hydrochloric Acid SCHEMBL6594509 | 0.75 | DPP4 (0.69) | DPP4DPP8 | |
| SCHEMBL6174984 | 0.75 | DPP4 (0.49) | DPP4ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6596405 | 0.74 | DPP4 (0.64) | DPP4 | |
| Hydrochloric Acid SCHEMBL5206594 | 0.73 | DPP4 (0.98) | DPP4 | |
| SCHEMBL647727 | 0.70 | DPP4 (0.59) | DPP4DPP8 | |
| SCHEMBL6167904 | 0.67 | DPP4 (0.66) | DPP4DPP8DPP7 | |
| SCHEMBL6488124 | 0.67 | DPP4 (0.66) | DPP4DPP8DPP7 | |
| SCHEMBL8072101 | 0.65 | ALDH1A1 (0.50) | DPP4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254113-A1 | N-SUBSTITUTED 2-CYANOPYROLES AND -PYRROLINES WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055105-A1 | N-SUBSTITUTED 2-CYANOPYROLES AND -PYRROLINES WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2001-08-02 | — | — | WO | disclosed |