SCHEMBL756416

SCHEMBL756416

OC[C@H](CC1CCCCC1)NCl

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRN P28799 1/20 0.36
SORT1 Q99523 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CNR2 P34972 1/20 0.33
CTSK P43235 2/20 0.32
METAP2 P50579 1/20 0.32
METAP1 P53582 1/20 0.32
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
CTSH P09668 1/20 0.32
MC4R P32245 1/20 0.32
MC3R P41968 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4716376 0.79 KMT2A (0.35) MEN1KMT2ACNR2CTSK
SCHEMBL4716380 0.79 MEN1 (0.41) MEN1KMT2ACTSKMETAP2CTSL
SCHEMBL16203420 0.79 MEN1 (0.41) MEN1KMT2ACTSKMETAP2CTSL
SCHEMBL23970178 0.79 MEN1 (0.41) MEN1KMT2ACTSKMETAP2CTSL
SCHEMBL13996915 0.78 MEN1 (0.40) MEN1KMT2ACTSKCTSLCTSB
SCHEMBL25589751 0.78 MEN1 (0.40) MEN1KMT2ACTSKCTSLCTSB
SCHEMBL25590340 0.77 MEN1 (0.39) MEN1KMT2ACNR2CTSKCTSL
SCHEMBL24530159 0.77 MEN1 (0.39) MEN1KMT2ACNR2CTSKCTSL
SCHEMBL23970350 0.75 MEN1 (0.38) MEN1KMT2ACNR2CTSKCTSL
SCHEMBL6826567 0.75 CTSK (0.36) MEN1KMT2ACTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138348-B2 Using coordination polymerization catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-03-20 US disclosed
US-20080182951-A1 Chromium Pyridine Bis(Oxazoline) And Related Catalysts For Ethylene Dimerization EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-31 US disclosed
US-20080182989-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Mono-Oxazoline Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-31 US disclosed
WO-2008085657-A1 CHROMIUM COMPLEXES OF PYRIDINE BIS (OXAZOLINE)- LIGANDS FOR ETHYLENE DIMERI ZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO disclosed
WO-2008085655-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE MONO-OXAZOLINE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182989-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Mono-Oxazoline Catalysts OXER1, OXGR1, OXA1L GRN 1571/4885SORT1 3809/4885MEN1 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.