SCHEMBL7564223

SCHEMBL7564223

C=C(C)C(=O)OCC(O)CC(F)(F)C(F)(F)CC(O)CO

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.34
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774854 0.94 TSHR (0.45) TSHRTHRBKDM4EDUSP3MEN1
SCHEMBL7772731 0.94 TSHR (0.45) TSHRTHRBKDM4EDUSP3MEN1
SCHEMBL247172 0.94 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL7771165 0.93 TSHR (0.44) TSHRTHRBKDM4EDUSP3MEN1
SCHEMBL7772722 0.93 TSHR (0.44) TSHRTHRBKDM4EDUSP3MEN1
SCHEMBL27495137 0.88 TSHR (0.51) TSHRTHRBALDH1A1
SCHEMBL247729 0.87 TSHR (0.41) TSHRTHRB
SCHEMBL248147 0.87 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL7767146 0.87 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL12128303 0.87 TSHR (0.50) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0857517-B1 METHOD OF FORMING COATING FILM NOF CORP (JP) 2002-08-21 EP disclosed
EP-0820980-B1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLIC ESTERS, FLUOROMONOMER COMPOSITION, MATERIAL WITH LOW REFRACTIVE INDEX, AND LOWLY REFLECTIVE FILM NOF CORP (JP) 2001-07-11 EP disclosed
US-6254973-B1 WEAR RESISTANCE NOF CORPORATION (JP) 2001-07-03 US disclosed
CN-1198106-A Method of forming coating film NOF CORP (JP) 1998-11-04 CN disclosed
EP-0857517-A1 METHOD OF FORMING COATING FILM NOF CORPORATION (JP) 1998-08-12 EP disclosed
CN-1189149-A Fluorine-containing polyfunctional (meth) acrylate, fluorine-containing monomer composition, low refractive index material, and antireflection film NIPPON OILS & FATS CO LTD (JP) 1998-07-29 CN disclosed
EP-0820980-A1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLIC ESTERS, FLUOROMONOMER COMPOSITION, MATERIAL WITH LOW REFRACTIVE INDEX, AND LOWLY REFLECTIVE FILM NOF CORPORATION (JP) 1998-01-28 EP disclosed