Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27104883 | 0.87 | LMNA (0.45) | LMNATAAR1SLC6A2RIPK1HTR2A | |
| SCHEMBL29010468 | 0.82 | LMNA (0.48) | LMNATAAR1SLC6A2RIPK1HTR2A | |
| SCHEMBL23252366 | 0.79 | TAAR1 (0.42) | LMNATAAR1SLC6A2RIPK1HTR2A | |
| Bromide SCHEMBL6520617 | 0.79 | LMNA (0.42) | LMNATAAR1HTR2AAOC3NOS3 | |
| SCHEMBL4592902 | 0.79 | LMNA (0.42) | LMNATAAR1HTR2AAOC3NOS3 | |
| Water SCHEMBL9711077 | 0.79 | LMNA (0.42) | LMNATAAR1HTR2AAOC3NOS3 | |
| SCHEMBL2679440 | 0.79 | LMNA (0.42) | LMNATAAR1HTR2AAOC3NOS3 | |
| SCHEMBL5425825 | 0.79 | LMNA (0.42) | LMNARIPK1SLC6A3 | |
| SCHEMBL6270809 | 0.78 | LMNA (0.45) | LMNARIPK1SLC6A3MIFCACNA1F | |
| SCHEMBL6270815 | 0.78 | LMNA (0.50) | LMNASLC6A2RIPK1AOC3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080866-A2 | USE OF ALVERINE FOR STIMULATING HAIR GROWTH | L'OREAL (FR) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002080877-A2 | USE OF ALVERINE OR ONE OF ITS SALTS | L'OREAL (FR) | 2002-10-17 | — | — | WO | disclosed |
| US-6335368-B1 | ADMINISTERING ALVERINE OR SALT COSMETIC TO SKIN AS MUSCLE RELAXANT; AGING RESISTANCE | SOCIETE L'OREAL S.A. (FR) | 2002-01-01 | — | — | US | disclosed |
| EP-1088548-A2 | Use of alverine for reducing wrinkles | L'OREAL (FR) | 2001-04-04 | — | — | EP | disclosed |