SCHEMBL75645

SCHEMBL75645

CC1(O)CNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL221036 0.96
Hydrochloric Acid SCHEMBL20703229 0.93
SCHEMBL14801159 0.82
SCHEMBL28345952 0.80
SCHEMBL860069 0.80
SCHEMBL20898974 0.77
Trifluoroacetic Acid SCHEMBL932054 0.76 PKM (0.30)
Hydrochloric Acid SCHEMBL23525863 0.75
SCHEMBL7553897 0.73
SCHEMBL2010663 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 844 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486260-B2 Indazolyl-isoxazole derivatives for the treatment of diseases such as cancer MERCK PATENT GMBH (DE) 2025-12-02 US claimed
CN-120025352-A Condensed heterocyclic compound, pharmaceutical composition and application thereof 北京康辰药业股份有限公司 2025-05-23 CN claimed
CN-116239597-B Pyrimidine pyrrole derivative and medicinal composition and application thereof 中国科学院上海药物研究所 2024-08-06 CN claimed
CN-110799190-B Heterocyclic compounds 卡都瑞恩医药有限公司 2024-04-19 CN claimed
CN-117881397-A Heterocyclic compounds and methods of use 安进公司 2024-04-12 CN claimed
WO-2024051766-A1 MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-03-14 WO claimed
EP-4329888-A1 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF Amgen Inc. (US) 2024-03-06 EP claimed
CN-117263940-A FGFR inhibitor, preparation method thereof, pharmaceutical composition and application 中国药科大学 2023-12-22 CN claimed
CN-111819176-B 4-azaindole compounds 百时美施贵宝公司 2023-12-15 CN claimed
CN-116348458-A Imidazolylpyrimidinylamine compounds as CDK2 inhibitors 因赛特公司 2023-06-27 CN claimed
CN-116239597-A Pyrimidine pyrrole derivative and medicinal composition and application thereof 中国科学院上海药物研究所 2023-06-09 CN claimed
CN-115996927-A Pyrimido [5,4-d ] pyrimidine derivatives and combinations with adenosine receptor antagonists as ENT inhibitors for the treatment of cancer ITEOS比利时公司 2023-04-21 CN claimed
WO-2022232332-A1 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF AMGEN INC. (US) 2022-11-03 WO claimed
US-20220127254-A1 INDAZOLYL-ISOXAZOLE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS CANCER MERCK PATENT GMBH (DE) 2022-04-28 US claimed
US-11274108-B2 Colony stimulating factor-1 receptor (CSF-1R) inhibitors GENZYME CORPORATION (US) 2022-03-15 US claimed
CN-105102449-B Antiviral compound 豪夫迈·罗氏有限公司 2017-06-13 CN claimed
US-12637454-B2 Heterocyclic monoacylglycerol lipase (MAGL) inhibitors HOFFMANN-LA ROCHE INC. (US) 2026-05-26 US disclosed
WO-2026102212-A1 MACROCYCLIC MCL-1 INHIBITORS VANDERBILT UNIVERSITY (US) 2026-05-15 WO disclosed
EP-0324298-B1 7-(1-AZETIDINYL)-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1992-12-23 EP disclosed
EP-0324298-A1 7-(1-Azetidinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic-acid derivatives, their preparation and their use as medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1989-07-19 EP disclosed