SCHEMBL7564560

SCHEMBL7564560

C[C@H]1OC(C(=O)O)(C(=O)O)O[C@H]1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.38
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7562888 1.00 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1
SCHEMBL7561121 1.00 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1
SCHEMBL7565873 1.00 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1
SCHEMBL7564372 0.82 SUCNR1 (0.47) SUCNR1KDM4EALDH1A1
SCHEMBL7569151 0.82 SUCNR1 (0.47) SUCNR1KDM4EALDH1A1
SCHEMBL7564729 0.82 SUCNR1 (0.47) SUCNR1KDM4EALDH1A1
SCHEMBL15325118 0.76 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1
SCHEMBL4871828 0.76 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1
SCHEMBL4243891 0.76 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1
SCHEMBL14527074 0.76 SUCNR1 (0.38) SUCNR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882703-B1 CYCLIC AMIC ACID DERIVATIVES BANYU PHARMA CO LTD (JP) 2002-08-14 EP disclosed
US-6011174-A INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-01-04 US disclosed
EP-0882703-A1 CYCLIC AMIC ACID DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-12-09 EP disclosed