Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564372 | 1.00 | SUCNR1 (0.47) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL7564729 | 1.00 | SUCNR1 (0.47) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL7562888 | 0.82 | SUCNR1 (0.38) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL7565873 | 0.82 | SUCNR1 (0.38) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL7564560 | 0.82 | SUCNR1 (0.38) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL7561121 | 0.82 | SUCNR1 (0.38) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL7561394 | 0.77 | SUCNR1 (0.33) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL28655535 | 0.73 | KDM4E (0.50) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL1595064 | 0.73 | SUCNR1 (0.45) | SUCNR1KDM4EALDH1A1 | |
| SCHEMBL10473227 | 0.73 | SUCNR1 (0.45) | SUCNR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |