Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564608 | 0.77 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL9000474 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL6566882 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL6566886 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL547926 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL1808375 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL1808376 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL754122 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16239168 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL9549187 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1MAPTALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230352-A2 | INHIBITORS OF VEGETABLE CYSTATHIONIN GAMMA SYNTHASE | Aventis CropScience GmbH (DE) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032849-A2 | INHIBITORS OF VEGETABLE CYSTATHIONIN GAMMA SYNTHASE | AVENTIS CROPSCIENCE GMBH (DE) | 2001-05-10 | — | — | WO | disclosed |