Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | BCL9 | O00512 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043134 | 0.89 | REN (0.39) | RENPPARGPPARABCL9CTNNB1 | |
| SCHEMBL6042304 | 0.87 | REN (0.49) | REN | |
| SCHEMBL6041813 | 0.85 | REN (0.48) | REN | |
| SCHEMBL6041854 | 0.83 | REN (0.47) | REN | |
| SCHEMBL6042924 | 0.82 | REN (0.47) | REN | |
| SCHEMBL6043142 | 0.82 | REN (0.43) | RENBCL9CTNNB1 | |
| SCHEMBL6041296 | 0.81 | REN (0.55) | REN | |
| SCHEMBL6043323 | 0.79 | REN (0.58) | REN | |
| SCHEMBL6041936 | 0.79 | REN (0.59) | RENPPARGPPARA | |
| SCHEMBL6042925 | 0.78 | REN (0.48) | RENPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |