Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561237 | 0.83 | NR5A1 (0.47) | RARBRARATP53HTR2CHTR2A | |
| SCHEMBL7925805 | 0.81 | RARB (0.54) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL7563652 | 0.81 | ALOX5 (0.48) | RARBALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL9419328 | 0.80 | RARB (0.54) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL9494751 | 0.79 | RARB (0.58) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL10535696 | 0.79 | RARB (0.58) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL10533738 | 0.79 | RARB (0.58) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL9497684 | 0.79 | RARB (0.58) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL9493565 | 0.79 | RARB (0.58) | RARBRARARARGESR1ADRA2A | |
| SCHEMBL9493854 | 0.79 | RARB (0.58) | RARBRARARARGESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944565-B1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-07-31 | — | — | EP | disclosed |