Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29236432 | 1.00 | PTPN1 (0.30) | PTPN1 | |
| Hydrochloric Acid SCHEMBL31343968 | 0.95 | PTPN1 (0.30) | PTPN1 | |
| Hydrochloric Acid SCHEMBL27739922 | 0.95 | PTPN1 (0.30) | PTPN1 | |
| SCHEMBL27940228 | 0.95 | — | — | |
| SCHEMBL30661142 | 0.95 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL28227557 | 0.95 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL407583 | 0.95 | — | — | |
| SCHEMBL15533446 | 0.95 | — | — | |
| SCHEMBL23828665 | 0.92 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL10395040 | 0.92 | PTPN1 (0.31) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072641-A1 | METHOD FOR MAKING AND USING A METALLOCENE CATALYST SYSTEM | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2002-09-19 | — | — | WO | claimed |
| US-6353071-B1 | DESICCATING MIXTURE OF ALUMINOXANE AND SOLVENT TO PRODUCE SOLID, MIXING WITH SOLVENT, CONTACTING SECOND MIXTURE WITH INSOLUBLIZATION AGENT TO PRODUCE ALUMINOXANE COMPOSITION, COMBINING WITH TRANSITION METAL CATALYST, POLYMERIZING OLEFIN | PHILLIPS PETROLEUM COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-0812860-B1 | Processes to produce organo-aluminoxane compositions | PHILLIPS PETROLEUM CO (US) | 2000-08-30 | — | — | EP | disclosed |
| US-6096915-A | Processes to produce organo-aluminoxane compositions | PALACKAL SYRIAC J (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0812860-A1 | Processes to produce organo-aluminoxane compositions | PHILLIPS PETROLEUM COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5480848-A | CONTAINING METALLOCENE AND REACTION PRODUCT OF ACIDIC HYDROGEN FREE ORGANIC BORANE AND ORGANOALUMINOXANE; ANTIFOULING, BROAD MOLECULAR WEIGHT DISTRIBUTION; POLYETTHYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5416179-A | Metallocene, isobutene | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5414180-A | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0634416-A1 | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0630900-A1 | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5354721-A | Organo-aluminoxy product and use | PHILLIPS PETROLEUM COMPANY (US) | 1994-10-11 | — | — | US | disclosed |