Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29291763 | 0.92 | MAPT (0.51) | MAPTKMT2AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL4217307 | 0.87 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4207600 | 0.87 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4210174 | 0.87 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4212205 | 0.87 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4208831 | 0.87 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL4204821 | 0.87 | MAPT (0.52) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| Butane SCHEMBL14935067 | 0.86 | POLB (0.54) | MAPTKMT2AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL22435386 | 0.85 | MEN1 (0.53) | MAPTKMT2AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL28124128 | 0.85 | MAPT (0.52) | MAPTKMT2AALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285849-A | Compound for targeted degradation of ALK, c-Met and ROS1 proteins and preparation method thereof | 上海青东生物科技有限公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-104945309-B | New nitroso compound and application thereof as nitroxyl donors | 卡尔迪奥克斯尔制药公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-102076342-B | Novel nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS INC | 2015-06-10 | — | — | CN | disclosed |
| CN-102076342-A | Novel nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS INC | 2011-05-25 | — | — | CN | disclosed |
| EP-1233968-A2 | TRANSITION METAL-CYCLOPENTADIENYL-TROPANE CONJUGATES | YALE UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-20020111486-A1 | Transition metal-cyclopentadienyl-tropane conjugates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-15 | — | — | US | disclosed |
| WO-2001040239-A2 | TRANSITION METAL-CYCLOPENTADIENYL-TROPANE CONJUGATES | YALE UNIVERSITY (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111486-A1 | Transition metal-cyclopentadienyl-tropane conjugates | SLC6A3, SLC18A2, SLC6A2 | MAPT 361/4885KMT2A 1943/4885ALDH1A1 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.