Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570162 | 1.00 | HPGD (0.48) | HPGDLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7567950 | 0.94 | HPGD (0.51) | HPGDLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1451542 | 0.81 | PTGER3 (0.50) | HPGDLMNASMN1; SMN2KMT2AHDAC3 | |
| SCHEMBL4287188 | 0.81 | PTGER3 (0.50) | HPGDLMNASMN1; SMN2KMT2AHDAC3 | |
| Hydrochloric Acid SCHEMBL9433691 | 0.79 | PTGER3 (0.49) | HPGDLMNASMN1; SMN2KMT2AHDAC3 | |
| SCHEMBL9433685 | 0.79 | PTGER1 (0.41) | SMN1; SMN2KMT2AALDH1A1MEN1POLB | |
| SCHEMBL9433677 | 0.79 | PTGER1 (0.41) | SMN1; SMN2KMT2AALDH1A1MEN1POLB | |
| SCHEMBL7565082 | 0.78 | KMT2A (0.51) | HPGDLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8415411 | 0.78 | PTPN1 (0.41) | SMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL8415409 | 0.78 | PTPN1 (0.41) | SMN1; SMN2EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934256-B1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | HONEYWELL INT INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0934256-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | AlliedSignal Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998016501-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | ALLIEDSIGNAL INC. (US) | 1998-04-23 | — | — | WO | disclosed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |