Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565080 | 0.94 | HPGD (0.48) | HPGDLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7570162 | 0.94 | HPGD (0.48) | HPGDLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1451542 | 0.84 | PTGER3 (0.50) | HPGDLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4287188 | 0.84 | PTGER3 (0.50) | HPGDLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9433685 | 0.82 | PTGER1 (0.41) | SMN1; SMN2KMT2AMEN1POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL9433691 | 0.82 | PTGER3 (0.49) | HPGDLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9433677 | 0.82 | PTGER1 (0.41) | SMN1; SMN2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8415411 | 0.81 | PTPN1 (0.41) | SMN1; SMN2ALDH1A1BACE1CD274PDCD1 | |
| SCHEMBL8415409 | 0.81 | PTPN1 (0.41) | SMN1; SMN2ALDH1A1BACE1CD274PDCD1 | |
| SCHEMBL39304 | 0.78 | ALDH1A1 (0.48) | HPGDLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934256-B1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | HONEYWELL INT INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0934256-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | AlliedSignal Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998016501-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | ALLIEDSIGNAL INC. (US) | 1998-04-23 | — | — | WO | disclosed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |