SCHEMBL756511

SCHEMBL756511

COC(=O)c1ccccc1SSc1ccccc1C(=O)OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.64
HSD17B10 Q99714 2/20 0.64
TSHR P16473 3/20 0.59
LMNA P02545 2/20 0.59
ALDH1A1 P00352 2/20 0.57
CFTR P13569 1/20 0.57
KDM4E B2RXH2 2/20 0.55
ATM Q13315 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MAPT P10636 2/20 0.54
PSMD14 O00487 1/20 0.53
PKLR P30613 1/20 0.51
KMT2A Q03164 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
ALOX15 P16050 1/20 0.50
MYC P01106 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30096217 1.00 POLB (0.64) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL4617374 0.93 POLB (0.71) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL11319693 0.92 POLB (0.60) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL11121116 0.92 POLB (0.60) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL12841780 0.88 POLB (0.56) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL4440485 0.88 HSD17B10 (0.64) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL647041 0.86 TSHR (0.71) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL7754027 0.86 HSD17B10 (0.62) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL18840127 0.86 POLB (0.61) POLBHSD17B10TSHRLMNAALDH1A1
SCHEMBL8624849 0.84 HSD17B10 (0.60) POLBHSD17B10TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024257830-A1 METHOD FOR PRODUCING AZULENE AND RELATED COMPOUNDS アルプス薬品工業株式会社 2024-12-19 WO claimed
CN-120059373-A Optical cable sheath material and preparation method thereof 深圳市达富光通信有限公司 2025-05-30 CN disclosed
WO-2024257830-A1 METHOD FOR PRODUCING AZULENE AND RELATED COMPOUNDS アルプス薬品工業株式会社 2024-12-19 WO disclosed
US-20240327576-A1 METHOD FOR MANUFACTURING SULFUR-CONTAINING POLYMER NIPPON SHOKUBAI CO., LTD. (JP) 2024-10-03 US disclosed
EP-4361200-A1 METHOD FOR MANUFACTURING SULFUR-CONTAINING POLYMER Nippon Shokubai Co., Ltd. (JP) 2024-05-01 EP disclosed
CN-117561293-A Process for producing sulfur-containing polymer 株式会社日本触媒 2024-02-13 CN disclosed
WO-2022270533-A1 METHOD FOR MANUFACTURING SULFUR-CONTAINING POLYMER 株式会社日本触媒 2022-12-29 WO disclosed
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
EP-2074091-B1 [2-(6-FLOURO-1H-INDOL-3-YLSULFANYL)BENZYL]METHYL AMINE FOR THE TREATMENT OF AFFECTIVE DISORDERS LUNDBECK & CO AS H (DK) 2015-01-07 EP disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
US-6201019-B1 ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION GALDERMA RESEARCH & DEVELOPMENT (FR) 2001-03-13 US disclosed
US-5342724-A Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
WO-1994011378-A1 ARYL THIOPYRANO[2,3,4-c,d]INDOLES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1994-05-26 WO disclosed
US-5314900-A Aryl thiopyrano[2,3,4-C,D]indoles as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA, INC. (CA) 1994-05-24 US disclosed
US-4307031-A DIAZOTIZATION THEN COPPER CATALYZED REACTION WITH CARBON DISULFIDE THE SHERWIN-WILLIAMS COMPANY (US) 1981-12-22 US disclosed
US-4303765-A PEPTIZATION WITH AROMATIC POLYSULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed
US-4110449-A ANTIINFLAMMATORY, SEDATIVE, MUSCLE RELAXANT E. R. SQUIBB & SONS, INC. (US) 1978-08-29 US disclosed
US-4085094-A SULFENYLTHIOCARBONATES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-04-18 US disclosed
US-4076721-A FROM PHOSGENE AND POTASSIUM OR CALCIUM METHYL BENZOATE-O-SULFONATE, AMMONIA, DMF IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1978-02-28 US disclosed
US-4057555-A FROM PHOSGENE AND O-SULFOBENZOIC ACID, DIMETHYLFORMAMIDE, ALCOHOL, AMMONIA IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1977-11-08 US disclosed