Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831926 | 0.90 | ELANE (0.40) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL8133240 | 0.90 | ELANE (0.40) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL10349639 | 0.90 | ELANE (0.37) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL10350771 | 0.86 | ELANE (0.38) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL10349838 | 0.85 | ELANE (0.37) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL8759627 | 0.83 | MEN1 (0.39) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL8759819 | 0.81 | MEN1 (0.38) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL10366328 | 0.81 | ELANE (0.49) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL8759130 | 0.81 | ELANE (0.49) | ELANEMEN1KMT2APTGS1 | |
| SCHEMBL8304069 | 0.81 | MEN1 (0.38) | ELANEMEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883620-B1 | PROCESS FOR THE PREPARATION OF 2-HALOMETHYL-PENEMS AND THEIR USE FOR THE PREPARATION OF ANTIBACTERIAL PENEMS | MENARINI FARMA IND (IT) | 2002-09-04 | — | — | EP | disclosed |
| US-6153747-A | Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 2000-11-28 | — | — | US | disclosed |
| EP-0883620-A1 | PROCESS FOR THE PREPARATION OF 2-HALOMETHYL-PENEMS AND THEIR USE FOR THE PREPARATION OF ANTIBACTERIAL PENEMS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031922-A1 | PROCESS FOR THE PREPARATION OF 2-HALOMETHYL-PENEMS AND THEIR USE FOR THE PREPARATION OF ANTIBACTERIAL PENEMS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1997-09-04 | — | — | WO | disclosed |
| EP-0236880-B1 | Penem derivatives | ERBA CARLO SPA (IT) | 1994-07-20 | — | — | EP | disclosed |
| US-4886793-A | PENICILLINS; HUMANS OR ANIMALS | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1989-12-12 | — | — | US | disclosed |
| EP-0236880-A2 | Penem derivatives | FARMITALIA CARLO ERBA S.r.l. (IT) | 1987-09-16 | — | — | EP | disclosed |