Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.70 |
| ▸ | ACE | P12821 | 12/20 | 0.70 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.49 |
| ▸ | CPA1 | P15085 | 5/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565208 | 1.00 | MME (0.70) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8446381 | 0.95 | MME (0.62) | MMEACECTSB | |
| SCHEMBL8032897 | 0.92 | MME (0.80) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8032600 | 0.92 | MME (0.80) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8017013 | 0.92 | MME (0.80) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8017006 | 0.92 | MME (0.80) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8028946 | 0.92 | MME (0.80) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL8017181 | 0.89 | MME (0.76) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL7572261 | 0.89 | MME (0.66) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL7570166 | 0.89 | MME (0.66) | MMEACEACE2CPA1GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |