Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.62 |
| ▸ | ACE | P12821 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565205 | 0.95 | MME (0.70) | MMEACECTSB | |
| SCHEMBL7565208 | 0.95 | MME (0.70) | MMEACECTSB | |
| SCHEMBL8447177 | 0.90 | MME (0.62) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL8446466 | 0.89 | MME (0.59) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL8450800 | 0.89 | MME (0.59) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL8446404 | 0.89 | MME (0.59) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL27442633 | 0.89 | MME (0.67) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL8446409 | 0.88 | MME (0.60) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL8451282 | 0.88 | MME (0.58) | MMEACECTSBTACR1MEN1 | |
| SCHEMBL27446784 | 0.88 | MME (0.66) | MMEACECTSBTACR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |