Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607565 | 0.90 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL7565227 | 0.75 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7572226 | 0.75 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8610813 | 0.72 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7569000 | 0.70 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7569466 | 0.70 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7568203 | 0.69 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7566106 | 0.69 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL8770202 | 0.69 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL1687503 | 0.69 | PTGS2 (0.79) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889878-B1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-09-04 | — | — | EP | claimed |
| EP-0889878-A1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1999-01-13 | — | — | EP | claimed |
| WO-1997036863-A1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-10-09 | — | — | WO | claimed |
| EP-0889878-B1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-09-04 | — | — | EP | disclosed |
| EP-0889878-A1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997036863-A1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-10-09 | — | — | WO | disclosed |