Hexane

Hexane

SCHEMBL7565319

CCCCCC.COCOC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 3/20 0.43
SLC22A1 O15245 3/20 0.39
SLC22A2 O15244 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DNM1 Q05193 5/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL16180639 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
Octane SCHEMBL27966378 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
Octane SCHEMBL27908920 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
Dimethoxymethane SCHEMBL9577611 0.84
Butyl Alcohol SCHEMBL7710487 0.81 ALDH1A1 (0.65) TSHRTHRBLMNASMN1; SMN2DNM1
Dimethoxymethane SCHEMBL22528640 0.81 TSHR (0.55) TSHRTHRBLMNASMN1; SMN2ALDH1A1
Hexane SCHEMBL5498517 0.79
Dimethoxymethane SCHEMBL27562420 0.79
Dimethoxymethane SCHEMBL8602889 0.79
SCHEMBL875853 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531475-B1 NAPHTHYL ORGANIC COMPOUNDS QINETIQ LTD (GB) 2002-08-28 EP disclosed
US-6291034-B1 LIQUID CRYSTALLINE MATERIAL THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 2001-09-18 US disclosed
US-5496500-A LIQUID CRYSTALS; ELECTROOPTICS DISPLAY DEVICES; DROPLETS DISPERSED IN TRANSPARENT POLYMER MATRIX THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN & NORTHERN IRELAND (GB) 1996-03-05 US disclosed