Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329813 | 0.91 | TSHR (0.55) | OPRM1OPRL1TSHRALOX15ATM | |
| SCHEMBL13543984 | 0.80 | TSHR (0.64) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL240381 | 0.80 | TSHR (0.57) | OPRM1OPRL1TSHRALOX15ATM | |
| SCHEMBL3246933 | 0.80 | TSHR (0.57) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL5415030 | 0.80 | TSHR (0.60) | TSHRALOX15ATMTACR1OPRD1 | |
| Hydrochloric Acid SCHEMBL7559118 | 0.79 | OPRM1 (0.53) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL972474 | 0.79 | TSHR (0.65) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL237234 | 0.79 | TSHR (0.56) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL10324681 | 0.79 | TSHR (0.56) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL9910972 | 0.78 | OPRM1 (0.71) | OPRM1OPRL1TACR1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915849-A2 | PROCESS FOR THE PREPARATION OF 3,3-DISUBSTITUTED PIPERIDINES | Smithkline Beecham S.p.A. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005640-A2 | PROCESS FOR THE PREPARATION OF 3,3-DISUBSTITUTED PIPERIDINES | SMITHKLINE BEECHAM S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |