SCHEMBL7565358

SCHEMBL7565358

CC(=O)Oc1cc(C)c(C)c(OC(C)=O)c1OC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.56
HTT P42858 2/20 0.54
KDM4E B2RXH2 6/20 0.45
ALDH1A1 P00352 5/20 0.45
MAPT P10636 4/20 0.45
GAA P10253 4/20 0.45
APEX1 P27695 2/20 0.45
RECQL P46063 2/20 0.45
BLM P54132 2/20 0.45
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TOP1 P11387 3/20 0.45
ACHE P22303 2/20 0.43
PTPN1 P18031 2/20 0.43
HSD17B10 Q99714 4/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 3/20 0.41
MAPK1 P28482 1/20 0.41
ALOX15 P16050 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14458328 0.88 POLB (0.56) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL2776573 0.86 POLB (0.57) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL2114307 0.85 POLB (0.53) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL14407309 0.84 HTT (0.59) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL15642113 0.84 POLB (0.65) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL12587225 0.83 POLB (0.51) POLBHTTKDM4EMAPTGAA
SCHEMBL10938410 0.83 POLB (0.49) POLBHTTKDM4EALDH1A1MAPT
Acetic Acid SCHEMBL7880506 0.82 POLB (0.50) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL2910532 0.82 POLB (0.62) POLBHTTKDM4EALDH1A1MAPT
SCHEMBL3293017 0.81 POLB (0.51) POLBHTTKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5340888-A Curable mixture of phenolic novolak resin, esterified phenolic compound and base; for foundry molds, cores BORDEN INC. (US) 1994-08-23 US claimed
EP-0377308-B1 Phenolic resins BORDEN UK LTD (GB) 1993-11-03 EP claimed
US-5051454-A An esterified phenolic compound, an unesterified phenolic resole and a base and curing BORDEN, INC. (US) 1991-09-24 US claimed
WO-1990006904-A2 PHENOLIC RESINS BORDEN (UK) LIMITED (GB) 1990-06-28 WO claimed
EP-1235656-A1 IMPROVEMENTS IN ESTER CURED BINDERS BORDEN CHEMICAL, INC. (US) 2002-09-04 EP disclosed
US-6232368-B1 USING ACIDIC METHYLENE COMPOUNDS IN BINDER COMPOSITIONS OF STRONGLY ALKALINE PHENOLIC RESOLES RESULTS IN ESTER CURABLE BINDER WHICH MAY BE USED TO MAKE FOUNDRY CORES AND MOLDS OF GREATER TENSILE STRENGTH BORDEN CHEMICAL, INC. 2001-05-15 US disclosed
WO-2001026842-A1 IMPROVEMENTS IN ESTER CURED BINDERS BORDEN CHEMICAL, INC. (US) 2001-04-19 WO disclosed
US-5294649-A Hardening agent of magnesioum hydroxide or lightburned magnesium oxide and promoter of a nitrogen-containing heterocyclic compound BORDEN, INC. (US) 1994-03-15 US disclosed
US-5281644-A Phenolic resin hardening with nitroalkane BORDEN, INC. (US) 1994-01-25 US disclosed
US-5262495-A Magnesium oxide or magnesium hydroxide hardeners to slow gelation BORDEN, INC. (US) 1993-11-16 US disclosed
EP-0377308-B1 Phenolic resins BORDEN UK LTD (GB) 1993-11-03 EP disclosed
US-5248707-A Phenolic resin solution and magnesia aggregate; ceramics, bricks BORDEN, INC. (US) 1993-09-28 US disclosed
US-5182347-A Hardening phenolic resin binder BORDEN, INC. (US) 1993-01-26 US disclosed
US-5182346-A Magnesium oxide or hydroxide, chelating agent BORDEN, INC. (US) 1993-01-26 US disclosed
US-5179177-A Binder for a magnesia aggregate BORDEN, INC. (US) 1993-01-12 US disclosed
US-5145913-A Decrease solubility of magnesium oxide or magnesium hydroxide hardener BORDEN, INC. (US) 1992-09-08 US disclosed
US-5096983-A Magnesium oxide and and ester as hardeners, retarder to inhibit hardening BORDEN, INC. (US) 1992-03-17 US disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 EP disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 EP disclosed