Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565543 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL11991815 | 0.81 | PSEN1 (0.51) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL26077272 | 0.80 | MCOLN3 (0.45) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL2600496 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL21552589 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1NPSR1GAA | |
| SCHEMBL12435190 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL6845966 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL6845965 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL12574213 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 | |
| SCHEMBL15304865 | 0.77 | MCOLN3 (0.45) | ALDH1A1KMT2ALMNAMCOLN3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3264928-B2 | — | — | 2002-03-11 | — | — | JP | claimed |
| EP-0638068-B1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER LAMBERT CO (US) | 1999-06-23 | — | — | EP | claimed |
| EP-0638068-A1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER-LAMBERT COMPANY (US) | 1995-02-15 | — | — | EP | claimed |
| WO-1993022283-A1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER-LAMBERT COMPANY (US) | 1993-11-11 | — | — | WO | claimed |
| US-5250704-A | Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines | WARNER-LAMBERT COMPANY (US) | 1993-10-05 | — | — | US | claimed |
| US-5177217-A | Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines | WARNER-LAMBERT COMPANY (US) | 1993-01-05 | — | — | US | claimed |
| EP-0638068-B1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER LAMBERT CO (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0911322-A2 | 1-Benzyl-3-(S)-[2-(S)-(tert-butoxy-carbonylamino) propionylamino] -pyrrolidine and its use as an intermediate | WARNER-LAMBERT COMPANY (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0638068-A1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER-LAMBERT COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993022283-A1 | PROCESS FOR THE MANUFACTURE OF (S)-3-AMINO-1-SUBSTITUTED-PYRROLIDINES | WARNER-LAMBERT COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
| US-5250704-A | Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines | WARNER-LAMBERT COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| US-5177217-A | Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines | WARNER-LAMBERT COMPANY (US) | 1993-01-05 | — | — | US | disclosed |