Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PNP | P00491 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | EDNRA | P25101 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.54 |
| ▸ | POLG | P54098 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244147 | 0.85 | MEN1 (0.71) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL7814355 | 0.80 | MEN1 (0.76) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL5449255 | 0.79 | MEN1 (0.69) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL29370760 | 0.78 | PNP (0.87) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL8445568 | 0.78 | MEN1 (0.73) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL14501172 | 0.77 | PNP (0.73) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL14501075 | 0.77 | PNP (0.73) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL14501173 | 0.76 | MEN1 (0.65) | MEN1KMT2AHBBMAPK1PNP | |
| Acyclovir SCHEMBL29531632 | 0.76 | PNP (0.97) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12088904 | 0.76 | PNP (0.71) | MEN1KMT2AHBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192129-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000061549-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | disclosed |