Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | CRHBP | P24387 | 2/20 | 0.74 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424800 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL7567158 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL35655 | 0.92 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3366384 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3705883 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL19680565 | 0.88 | LMNA (0.63) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL23658043 | 0.86 | LMNA (1.00) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL687476 | 0.86 | LMNA (1.00) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL10025196 | 0.86 | LMNA (1.00) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL76331 | 0.86 | LMNA (1.00) | SMN1; SMN2LMNACRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274129-A | Hydroxamic acid crown ethers | IDAHO RESEARCH FOUNDATION, INC. (US) | 1993-12-28 | — | — | US | claimed |
| US-5225173-A | Chelation, crown ethers | IDAHO RESEARCH FOUNDATION, INC. (US) | 1993-07-06 | — | — | US | claimed |
| EP-0762918-B1 | FLUID EXTRACTION OF METALS AND/OR METALLOIDS | IDAHO RES FOUND (US) | 2002-08-28 | — | — | EP | disclosed |
| US-5965025-A | DETOXIFICATION BY SOLVENT EXTRACTING METALLOID AND METAL SPECIES FROM A SOLID OR LIQUID MATERIAL BY A SUPERCRITICAL FLUID SOLVENT CONTAINING A CHELATING AGENT, FORMING CHELATES THAT ARE SOLUBLE IN THE SUPERCRITICAL FLUID | IDAHO RESEARCH FOUNDATION, INC. (US) | 1999-10-12 | — | — | US | disclosed |
| US-5770085-A | CARBON DIOXIDE, CHELATING AGENT COMPRISING A PHOSPHATE OR A PHOSPHINE OXIDE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5730874-A | Extraction of metals using supercritical fluid and chelate forming legand | IDAHO RESEARCH FOUNDATION, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0762918-A1 | FLUID EXTRACTION OF METALS AND/OR METALLOIDS | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033541-A1 | FLUID EXTRACTION OF METALS AND/OR METALLOIDS | IDAHO RESEARCH FOUNDATION, INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5356538-A | Removing a metalloid or metal species from solid or liquid using a fluorinated chelating agent | IDAHO RESEARCH FOUNDATION, INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5274129-A | Hydroxamic acid crown ethers | IDAHO RESEARCH FOUNDATION, INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-5225173-A | Chelation, crown ethers | IDAHO RESEARCH FOUNDATION, INC. (US) | 1993-07-06 | — | — | US | disclosed |
| US-3956136-A | HYDROPHILIC SEMIPERMEABLE MEMBRANE | UNION CARBIDE CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |