Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569011 | 0.88 | RAD52 (0.59) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7567212 | 0.88 | AOX1 (0.49) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7566347 | 0.88 | HDAC1 (0.67) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7564176 | 0.88 | AOX1 (0.56) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7567238 | 0.86 | RAD52 (0.47) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7567270 | 0.86 | RAD52 (0.61) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7565910 | 0.85 | RAD52 (0.55) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL8413271 | 0.84 | RAD52 (0.57) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL7565771 | 0.83 | AOX1 (0.63) | AOX1HTTHDAC1HDAC6RAD52 | |
| SCHEMBL14440618 | 0.83 | HDAC1 (0.61) | AOX1HTTHDAC1HDAC6RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |