Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 3/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566738 | 0.96 | MAPT (0.48) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7566425 | 0.90 | MAPT (0.51) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7564995 | 0.88 | TAS1R3 (0.41) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7566996 | 0.87 | TAS1R3 (0.49) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7565063 | 0.85 | MAPT (0.41) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7565793 | 0.85 | MAPT (0.40) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7566548 | 0.85 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7568879 | 0.85 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL7564172 | 0.84 | TAS1R3 (0.41) | MAPTKMT2AKDM4EATMTAS1R3 | |
| SCHEMBL7567031 | 0.83 | TAS1R3 (0.48) | MAPTCYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |