Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281905 | 0.70 | APOBEC3A (0.37) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL5944513 | 0.69 | APOBEC3A (0.40) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL15293601 | 0.65 | CYP1A2 (0.43) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL7074944 | 0.64 | CYP3A4 (0.41) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Iodide SCHEMBL3636049 | 0.62 | POLB (0.42) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| Hydrochloric Acid SCHEMBL8022255 | 0.62 | CYP3A4 (0.39) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL1641599 | 0.62 | — | — | |
| Cyanamide SCHEMBL15435940 | 0.61 | CHRM2 (0.32) | CHRNA7CYP3A4ALOX15CHRNB2NFKB1 | |
| SCHEMBL7938935 | 0.61 | — | — | |
| Iodide SCHEMBL22032686 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911417-B1 | Enzyme-based assay for determining effects of exogenous and endogenous factors on cellular energy production | BIRKMAYER PHARMACEUTICALS INC (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6383771-B1 | MIXING SAMPLE OF WHOLE BLOOD FROM SUBJECT WHICH INCLUDES ENDOGENOUS OXIDOREDUCTASE WITH SUBSTRATE FOR THE ENZYME, MEASURING AMOUNT OF SUBSTRATE REDUCED, AND CORRELATING THAT AMOUNT WITH ENERGY PRODUCING CAPACITY OF CELLS IN SAMPLE | BIRKMAYER PHARMACEUTICALS | 2002-05-07 | — | — | US | disclosed |
| US-6248552-B1 | ADDING REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE TO SAMPLE OF WHOLE BLOOD CONTAINING ENDOGENOUS OXIDOREDUCTASE, MEASURING AMOUNT OXIDIZED, THEN CORRELATING AMOUNT WITH ENERGY CAPACITY OF CELLS IN SAMPLE | BIRKMAYER PHARMACEUTICALS | 2001-06-19 | — | — | US | disclosed |
| EP-0911417-A2 | Enzyme-based assay for determining effects of exogenous and endogenous factors on cellular energy production | Birkmayer Pharmaceuticals, Inc. (US) | 1999-04-28 | — | — | EP | disclosed |