Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.54 |
| ▸ | ACE | P12821 | 4/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575157 | 0.91 | MME (0.66) | MMEACECTSSCTSKCPA1 | |
| SCHEMBL7570374 | 0.88 | MME (0.62) | MMEACEMMP9MMP8MMP2 | |
| SCHEMBL8448671 | 0.88 | MME (0.53) | MMEACECTSSCTSKPSEN1 | |
| SCHEMBL8449573 | 0.87 | MME (0.52) | MMEACECTSSCTSKPSEN1 | |
| SCHEMBL7569084 | 0.86 | MME (0.60) | MMEACEMMP9MMP8MMP2 | |
| SCHEMBL8447424 | 0.85 | MME (0.54) | MMEACECTSSCTSKMMP9 | |
| SCHEMBL8446415 | 0.84 | MME (0.53) | MMEACECTSSCTSKMMP9 | |
| SCHEMBL7567643 | 0.82 | MME (0.52) | MMEACECTSSCTSKMMP9 | |
| SCHEMBL27464914 | 0.81 | MME (0.57) | MMEACECTSSCTSKMMP9 | |
| SCHEMBL27464915 | 0.81 | MME (0.57) | MMEACECTSSCTSKMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |