Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.60 |
| ▸ | ACE | P12821 | 4/20 | 0.60 |
| ▸ | MMP9 | P14780 | 8/20 | 0.54 |
| ▸ | MMP2 | P08253 | 8/20 | 0.54 |
| ▸ | MMP8 | P22894 | 7/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 3/20 | 0.47 |
| ▸ | FCER2 | P06734 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570374 | 0.93 | MME (0.62) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL7570165 | 0.92 | MME (0.71) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL8447424 | 0.86 | MME (0.54) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL7566539 | 0.86 | MME (0.54) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL8027274 | 0.86 | MME (0.74) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL8033048 | 0.85 | MME (0.83) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL8033058 | 0.85 | MME (0.83) | MMEACEMMP9MMP2MMP8 | |
| SCHEMBL7568906 | 0.83 | MME (0.77) | MMEACECPA1ACE2 | |
| SCHEMBL7567925 | 0.83 | MME (0.77) | MMEACECPA1ACE2 | |
| SCHEMBL7567517 | 0.83 | MME (0.77) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |