Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTB | P49356 | 16/20 | 0.42 |
| ▸ | FNTA | P49354 | 15/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238053 | 0.81 | FNTA (0.40) | FNTBFNTAPGGT1B | |
| SCHEMBL7694904 | 0.80 | FNTB (0.39) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7701717 | 0.80 | FNTB (0.39) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7589567 | 0.80 | FNTB (0.39) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7244089 | 0.80 | FNTA (0.41) | FNTBFNTAPGGT1B | |
| SCHEMBL7222091 | 0.80 | FNTA (0.47) | FNTBFNTAPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7220637 | 0.79 | FNTA (0.47) | FNTBFNTAPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7672909 | 0.78 | CYP17A1 (0.48) | FNTBFNTAPGGT1BRORCCYP11B1 | |
| SCHEMBL7244096 | 0.76 | FNTA (0.38) | FNTBFNTAPGGT1B | |
| SCHEMBL7566589 | 0.75 | FNTA (0.44) | FNTBFNTAPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079147-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002078702-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-10-10 | — | — | WO | disclosed |