Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTB | P49356 | 15/20 | 0.39 |
| ▸ | FNTA | P49354 | 14/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 14/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589567 | 1.00 | FNTB (0.39) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7694904 | 1.00 | FNTB (0.39) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7736917 | 0.87 | FNTA (0.37) | FNTBFNTAPGGT1BRORC | |
| SCHEMBL7582554 | 0.87 | FNTB (0.34) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7566587 | 0.80 | FNTB (0.42) | FNTBFNTAPGGT1BSIGMAR1HRH1 | |
| SCHEMBL7736898 | 0.80 | PKM (0.35) | FNTBFNTAPGGT1B | |
| Hydrochloric Acid SCHEMBL7758000 | 0.77 | PKM (0.33) | FNTBFNTAPGGT1B | |
| SCHEMBL7672909 | 0.75 | CYP17A1 (0.48) | FNTBFNTAPGGT1BRORC | |
| SCHEMBL7228124 | 0.73 | CYP11B1 (0.36) | FNTBFNTAPGGT1B | |
| SCHEMBL7673750 | 0.71 | FNTA (0.44) | FNTBFNTAPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020015-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-03-14 | — | — | WO | disclosed |