Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566625 | 1.00 | KDM4E (0.53) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7560310 | 0.85 | MAPT (0.50) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7560304 | 0.85 | MAPT (0.50) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7562077 | 0.83 | SMN1; SMN2 (0.51) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7562081 | 0.83 | SMN1; SMN2 (0.51) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6681611 | 0.82 | SMN1; SMN2 (0.50) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7530209 | 0.81 | RAB9A (0.46) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7530215 | 0.81 | RAB9A (0.46) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5387973 | 0.76 | SMN1; SMN2 (0.49) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7559877 | 0.75 | SMN1; SMN2 (0.48) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |