Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28092833 | 0.88 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL28362744 | 0.78 | CHRM2 (0.35) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL1027531 | 0.78 | AAK1 (0.34) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL24125452 | 0.77 | CA14 (0.37) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL7320870 | 0.77 | MEN1 (0.50) | HDAC1HDAC2 | |
| SCHEMBL3469119 | 0.76 | CA14 (0.46) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL1067066 | 0.76 | CA14 (0.38) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL4267839 | 0.76 | AAK1 (0.33) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL13215105 | 0.76 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CA14CA1 | |
| SCHEMBL25736664 | 0.74 | CA14 (0.34) | HDAC6HDAC1HDAC2CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |