Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | CTSL | P07711 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096540 | 1.00 | CTSK (0.44) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5096536 | 1.00 | CTSK (0.44) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6762056 | 0.90 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6762057 | 0.90 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6740606 | 0.89 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6740612 | 0.89 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7036592 | 0.86 | CTSK (0.51) | CTSKCTSLCTSSKMT2ACACNA1B | |
| SCHEMBL4902191 | 0.86 | CTSK (0.51) | CTSKCTSLCTSSKMT2ACACNA1B | |
| SCHEMBL5099105 | 0.84 | CTSK (0.47) | CTSKMAPK1 | |
| SCHEMBL5099103 | 0.84 | CTSK (0.47) | CTSKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |