Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491982 | 0.84 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL7566915 | 0.77 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7596762 | 0.75 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7566920 | 0.75 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7493730 | 0.75 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL7488615 | 0.75 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL7590849 | 0.73 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL7592819 | 0.73 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL5356924 | 0.70 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL7485889 | 0.69 | CRHR1 (0.63) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233949-A2 | 5-SUBSTITUTED ARYLPYRIMIDINES | NEUROGEN CORPORATION (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001068614-A2 | 5-SUBSTITUTED ARYLPYRIMIDINES | NEUROGEN CORPORATION (US) | 2001-09-20 | — | — | WO | disclosed |