Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780897 | 1.00 | KDM4E (0.35) | KDM4ETSHRTDP1 | |
| SCHEMBL465571 | 1.00 | KDM4E (0.35) | KDM4ETSHRTDP1 | |
| SCHEMBL7780906 | 1.00 | KDM4E (0.35) | KDM4ETSHRTDP1 | |
| SCHEMBL6657771 | 0.90 | KDM4E (0.38) | KDM4ETSHRTDP1 | |
| SCHEMBL11525767 | 0.81 | — | — | |
| SCHEMBL5965345 | 0.81 | — | — | |
| SCHEMBL834357 | 0.78 | KDM4E (0.31) | KDM4ETSHRTDP1 | |
| SCHEMBL1824498 | 0.78 | TSHR (0.42) | KDM4ETSHRTDP1 | |
| SCHEMBL5489726 | 0.78 | TSHR (0.42) | KDM4ETSHRTDP1 | |
| SCHEMBL1824897 | 0.78 | TSHR (0.42) | KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| EP-0890131-A2 | PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS | ALLIANT TECHSYSTEMS INC. (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1998052990-A1 | FLUORINATED AMINE PRODUCTS | ALLIANT TECHSYSTEMS INC. (US) | 1998-11-26 | — | — | WO | disclosed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | disclosed |
| WO-1997037273-A2 | PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS | ALLIANT TECHSYSTEMS INC. (US) | 1997-10-09 | — | — | WO | disclosed |