Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570267 | 0.86 | MYC (0.44) | RXRARXRBRXRGPTGER1AGTR1 | |
| SCHEMBL7565426 | 0.82 | AGTR1 (0.41) | RXRARXRBRXRGPTGER1AGTR1 | |
| SCHEMBL9177572 | 0.78 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9173092 | 0.77 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9173833 | 0.77 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9172143 | 0.77 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9025182 | 0.77 | AGTR1 (0.49) | AGTR1AGTR2CYP2C9 | |
| SCHEMBL9661454 | 0.76 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9177493 | 0.76 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9177563 | 0.75 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |