Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233252 | 0.84 | TSHR (0.44) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL11365890 | 0.81 | TSHR (0.55) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL8031428 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL28840980 | 0.75 | POLB (0.58) | ALDH1A1HSD17B10KDM4ETDP1POLB | |
| SCHEMBL22486452 | 0.75 | KDM4E (0.40) | ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8741344 | 0.74 | POLB (0.49) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL6419163 | 0.72 | TSHR (0.46) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL15724550 | 0.72 | TSHR (0.46) | ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2 | |
| SCHEMBL7631413 | 0.72 | POLB (0.62) | ALDH1A1KDM4ETDP1AKR1C3POLB | |
| SCHEMBL5004427 | 0.72 | HAO1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436544-B1 | METAL LAYERS ON POLYVINYL ALCOHOL AND POLYESTERS | TORAY PLASTICS EUROPE S.A. (FR) | 2002-08-20 | — | — | US | disclosed |
| US-6420004-B1 | BIAXIAL STRETCHING | TORAY PLASTICS EUROPE S.A. (FR) | 2002-07-16 | — | — | US | disclosed |
| US-20020028295-A1 | Composite metal-coated polyester films with barrier properties | VEYRAT DIDIER (FR) | 2002-03-07 | — | — | US | disclosed |
| US-6300306-B1 | TREATING HARD SURFACES, POLYOXYALKYLENE UNITS AND SULFONATEDPOLYAMIDES AND SULFONATED POLYFUNCTIONAL UNITS AND BINDING GROUPS WITH ESTER | RHODIA CHIMIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-5290631-A | Terephthalate, isophthalate, sulfoaryl dicarboxylate, ethylene glycol and polyoxyethylene glycol units; glass transition temperature, turbidity, storage stability; preparation by transesterification, direct esterification, polycondensation | RHONE-POULENC CHIMIE (FR) | 1994-03-01 | — | — | US | disclosed |