Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL5675621 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL9573257 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL21081157 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL10732239 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL11581089 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL11407115 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL8652348 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL10833194 | 0.97 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL15662929 | 0.97 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL11873328 | 0.97 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113759065-B | Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method | 北京康仁堂药业有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-113759065-A | Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method | 北京康仁堂药业有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-104277085-A | Method for simultaneously separating four sedum purpureum flavones by employing online two-dimensional serial chromatography technology | UNIV JIANGNAN | 2015-01-14 | — | — | CN | claimed |
| CN-103585193-A | Application of Aleuritopteris argentea Fee extract in preparation of drugs treating leukemia | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-100434135-C | Method for separating and purifying natural product using three-phase counter current chromatograph | PROCESS ENG INST CAS (CN) | 2008-11-19 | — | — | CN | claimed |
| CN-1935309-A | Method for separating and purifying natural product using three-phase counter current chromatograph | PROCESS ENG INST CAS (CN) | 2007-03-28 | — | — | CN | claimed |
| US-20060204589-A1 | Bear derived isolate and method | NELSON RALPH A | 2006-09-14 | — | — | US | claimed |
| US-7060300-B2 | Bear derived isolate and method | CARLE DEVELOPMENT FOUNDATION (US) | 2006-06-13 | — | — | US | claimed |
| US-20040209851-A1 | Bear derived isolate and method | NELSON RALPH A (US) | 2004-10-21 | — | — | US | claimed |
| US-20240157333-A1 | PICOSCALE THIN LAYER CHROMATOGRAPHY FOR ANALYSIS OF SINGLE CELLS AND MICROSAMPLES | UNIVERSITY OF WASHINGTON (US) | 2024-05-16 | — | — | US | disclosed |
| CN-113759065-B | Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method | 北京康仁堂药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113759065-B | Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method | 北京康仁堂药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20220411748-A1 | CELL CULTURE MEDIA | MERCK PATENT GMBH (DE) | 2022-12-29 | — | — | US | disclosed |
| US-20210395717-A1 | RECOMBINANT HOST CELL FOR PRODUCING BENZYLISOQUINOLINE ALKALOID (BIA) AND NOVEL METHOD FOR PRODUCING BENZYLISOQUINOLINE ALKALOID (BIA) | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2021-12-23 | — | — | US | disclosed |
| EP-0000167-A1 | 1,2,3,6-Tetrahydroisonicotinic acid and derivatives thereof, methods and starting products for their preparation, and pharmaceutical compositions containing them. | Krogsgaard-Larsen, Povl (DK) | 1979-01-10 | — | — | EP | disclosed |
| US-4128540-A | Pyroglutamyl-histidyl-tryptophanyl-seryl-tyrosyl hydrazides | PARKE, DAVIS & COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4124578-A | ANTIFERTILITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4011207-A | Des-(Ala1, Gly2,Lys4 -Srif, Des-(Ala1, Gly2, Lys4)-D-Trp8 -Srif and intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
| US-3948885-A | ANTIVIRAL | ICN PHARMACEUTICALS, INC. (US) | 1976-04-06 | — | — | US | disclosed |
| US-3931140-A | (H-gly-gly-tyr-ala)1 -somatostatin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |