Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886397 | 0.85 | ALDH1A1 (0.58) | ALDH1A1RAD52ALBDHODHKDM4E | |
| SCHEMBL30548734 | 0.83 | ALDH1A1 (0.88) | ALDH1A1DHODHKDM4EHPGDRAB9A | |
| SCHEMBL68995 | 0.83 | ALDH1A1 (0.88) | ALDH1A1DHODHKDM4EHPGDRAB9A | |
| Phenazine-1-Carboxylic Acid SCHEMBL28160016 | 0.82 | ALDH1A1 (1.00) | ALDH1A1DHODHKDM4EHPGDRAB9A | |
| Phenazine-1-Carboxylic Acid SCHEMBL27884214 | 0.82 | ALDH1A1 (1.00) | ALDH1A1DHODHKDM4EHPGDRAB9A | |
| Phenazine-1-Carboxylic Acid SCHEMBL29370801 | 0.82 | ALDH1A1 (1.00) | ALDH1A1DHODHKDM4EHPGDRAB9A | |
| Phenazine-1-Carboxylic Acid SCHEMBL122864 | 0.82 | ALDH1A1 (1.00) | ALDH1A1DHODHKDM4EHPGDRAB9A | |
| SCHEMBL30468172 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDRAB9ANAPRT | |
| SCHEMBL3724658 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDRAB9ANAPRT | |
| Phenazine-1-Carboxylic Acid SCHEMBL28714733 | 0.80 | ALDH1A1 (0.96) | ALDH1A1DHODHKDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |