Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939483 | 0.86 | PAOX (0.33) | ALDH1A1POLBKDM4EKMT2ATP53 | |
| SCHEMBL6365195 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1ALDH1A1POLBKDM4E | |
| SCHEMBL21939486 | 0.84 | MAPT (0.37) | CHRM2CHRM1ALDH1A1HTTKMT2A | |
| SCHEMBL21939493 | 0.84 | MAPT (0.40) | CHRM2CHRM1ALDH1A1HTTKMT2A | |
| SCHEMBL21939069 | 0.82 | MAPT (0.42) | ALDH1A1POLBHTTKMT2ATP53 | |
| SCHEMBL21939489 | 0.82 | MAPT (0.42) | ALDH1A1POLBHTTKMT2ATP53 | |
| SCHEMBL7618980 | 0.80 | ALDH1A1 (0.42) | CHRM2CHRM1ALDH1A1KDM4ELMNA | |
| SCHEMBL21939487 | 0.79 | GAA (0.31) | ALDH1A1 | |
| SCHEMBL647080 | 0.79 | ALDH1A1 (0.44) | CHRM2CHRM1ALDH1A1POLBKDM4E | |
| SCHEMBL21939494 | 0.79 | MEN1 (0.44) | ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083938-A2 | SCREENING METHODS FOR IDENTIFYING LIGANDS | EMERALD BIOSTRUCTURES, INC. (US) | 2002-10-24 | — | — | WO | disclosed |