Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565847 | 0.86 | MAPT (0.37) | LMNASMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL7571240 | 0.83 | PDE3B (0.34) | SMN1; SMN2ALDH1A1CYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL7566886 | 0.82 | PDE3B (0.33) | SMN1; SMN2ALDH1A1CYP3A4TDP1PDE3B | |
| SCHEMBL7567678 | 0.79 | PDE3B (0.32) | PDE3BPDE3A | |
| SCHEMBL7567254 | 0.76 | PLAU (0.42) | SMN1; SMN2ALDH1A1CYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL7566216 | 0.74 | F2 (0.44) | SMN1; SMN2ALDH1A1CYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL7565620 | 0.74 | F2 (0.44) | SMN1; SMN2ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL22270622 | 0.70 | ALDH1A1 (0.46) | LMNASMN1; SMN2PSMD14ALDH1A1CYP3A4 | |
| SCHEMBL10726634 | 0.69 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4TSHR | |
| SCHEMBL14134218 | 0.69 | HCRTR1 (0.44) | LMNASMN1; SMN2ALDH1A1MAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492502-B2 | REDUCTION OF A QUATERNARY AMMONIUM CONTAINING NITRO COMPOUND, TO FORM AN INTERMEDIATE, OXIDIZING TO GIVE AZO COMPOUND; USEFUL FOR DYEING HAIR | L'OREAL, S.A. (FR) | 2002-12-10 | — | — | US | claimed |
| US-20020165368-A1 | Novel azo compounds, use in dyeing, compositions containing them and dyeing processes | L'OREAL S.A. | 2002-11-07 | — | — | US | claimed |
| US-20010001332-A1 | Novel azo compounds, use in dyeing, compositions containing them and dyeing processes | L'OREAL S.A. | 2001-05-24 | — | — | US | claimed |
| US-6492502-B2 | REDUCTION OF A QUATERNARY AMMONIUM CONTAINING NITRO COMPOUND, TO FORM AN INTERMEDIATE, OXIDIZING TO GIVE AZO COMPOUND; USEFUL FOR DYEING HAIR | L'OREAL, S.A. (FR) | 2002-12-10 | — | — | US | disclosed |
| US-20020165368-A1 | Novel azo compounds, use in dyeing, compositions containing them and dyeing processes | L'OREAL S.A. | 2002-11-07 | — | — | US | disclosed |
| US-6179881-B1 | USING (DIAZINE OR HYDRAZINE)CARBOXIMIDAMIDE COMPOUNDS | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010001332-A1 | Novel azo compounds, use in dyeing, compositions containing them and dyeing processes | KRT18, MKI67, KDM5A | LMNA 497/4885SMN1; SMN2 4705/4885PSMD14 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.