Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.64 |
| ▸ | ACE | P12821 | 11/20 | 0.64 |
| ▸ | CPA1 | P15085 | 4/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.47 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572405 | 0.95 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7572401 | 0.95 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7568387 | 0.95 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7567269 | 0.95 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7569081 | 0.92 | MME (0.57) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL7569082 | 0.92 | MME (0.57) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL7570079 | 0.91 | MME (0.58) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL7565980 | 0.90 | MME (0.70) | MMEACECPA1ACE2 | |
| SCHEMBL7565973 | 0.90 | MME (0.70) | MMEACECPA1ACE2 | |
| SCHEMBL7566033 | 0.89 | MME (0.69) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |