Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.57 |
| ▸ | ACE | P12821 | 11/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569081 | 1.00 | MME (0.57) | MMEACEMMP2MMP3CPA1 | |
| SCHEMBL7567435 | 0.92 | MME (0.64) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL7568408 | 0.92 | MME (0.52) | MMEACEMMP2MMP3CPA1 | |
| SCHEMBL7568400 | 0.92 | MME (0.52) | MMEACEMMP2MMP3CPA1 | |
| SCHEMBL7568387 | 0.89 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7572401 | 0.89 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7572405 | 0.89 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7567269 | 0.89 | MME (0.71) | MMEACECPA1ACE2 | |
| SCHEMBL7567827 | 0.88 | MME (0.73) | MMEACEMMP2CPA1ACE2 | |
| SCHEMBL7567832 | 0.88 | MME (0.73) | MMEACEMMP2CPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |