Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567576 | 1.00 | GABRA1 (0.33) | GABRA1GABRB2CTSSCTSKBACE1 | |
| SCHEMBL7567599 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2BACE1 | |
| SCHEMBL8993629 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2BACE1 | |
| SCHEMBL7564526 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2BACE1 | |
| SCHEMBL8993464 | 0.74 | TAAR1 (0.33) | — | |
| SCHEMBL4583472 | 0.73 | ATM (0.36) | — | |
| SCHEMBL8406168 | 0.73 | ATM (0.36) | — | |
| SCHEMBL8402080 | 0.73 | ATM (0.36) | — | |
| SCHEMBL4950480 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2CTSSCTSK | |
| SCHEMBL8228214 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-B1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | UNIV OHIO STATE RES FOUND (US) | 2002-09-04 | — | — | EP | disclosed |
| US-5504108-A | ANTIAGGLOMERANTS, ANTIARTHRITIC AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |